Kajian Pure Marine Collagent Eucheuma Cottonni
Hasil kajian daripada seorang penyelidik daripada Universiti Malaysia Sabah, Profesor Ismail Abdul Rahman telahpun diiktiraf oleh Lembaga Kemajuan Ikan Malaysia(LKIM) dimana beliau merupakan salah seorang penyelidik dalam Projek Pembangunan Industri Rumpai Laut Negara.
Profesor Ismail Abdul Rahman membuat penyelidikan rumpai laut menggunakan syarikat beliau sebelum ini iaitu Borneo Sein Sdn Bhd. Pilot project ini dipantau dan dibiayai oleh Lembaga Kemajuan Ikan Malaysia (LKIM). Kini, beliau telah menubuhkan syarikat baru iaitu Aquamas Sdn Bhd.
Potensi Pasaran Rumpai Laut
Setakat januari 2009, telah dikenal pasti sejumlah 1067 jenis produk dapat dihasilkan dengan rumpai laut. Antara produk tersebut adalah sebagai bahan makanan kesihatan, perubatan, industri kimia, cat, kecantikan dan lain-lain. Permintaan (demand) rumpai laut adalah sangat jauh berbanding penawaran (supply), oleh itu potensi industri ini adalah sangat cerah.
Kajian Pure Marine Collagent Eucheuma Cottonni
Spesis rumpai laut yang paling lengkap dan serasi dengan tubuh badan manusia adalahEucheuma Cottonni.
Komposisi Pemakanan Eucheuma Cottonni
Oleh: P. Matanjun, S. Mohamed, K. Muhammad & N. M. Mustapha (University Sains Malaysia, Sabah, University Puetra Malaysia, Serdang)
Serat Pemakanan, Karbohidrat, Protein, Asid Lemak, Garam Elektrolit, Garam Mikro, Vitamin B Kompleks, A, C, D dan lain lain lagi.
Serat Pemakanan: 25.05%
a) Serat Larut – 18.25% – Agar, Carrageenan, Sulfated Xylans dan lain lain lagi.
b) Serat Tidak Larut – 6.80% – Cellouse, Mannans.
Faedah Dan Aplikasi
Kebanyakan Serat Terlarut berkesan untuk merendahkan paras kolesterol dan paras gula dalam darah, amat sesuai untuk mencegah penyakit jantung. Serat Terlarut juga dilihat sebagai makanan yang mempunyai fungsi baik bagi mencegah gejala metabolisma gula, amat berkesan untuk mencegah Diabetes. Manakala kesan Serat Tidak Larut lazimnya mempercepatkan pergerakan saluran penghadaman.
Serat Pejal – 5.91%
Seperti kanji Floridean, Iso-Floridoside, Sorbitol.
Faedah Dan Aplikasi
Sorbitol dirujuk sebagai pemanis pemakanan kerana ia memberi tenaga 2.6 kilokalori (11kilojoules /gram). Ia juga bertindak untuk menarik air ke dalam usus besar bagi merangsang pergerakan usus serta pembuangan sisa pepejal. Amat berguna bagi pembersihan usus , khususnya untuk mencegah perut buncit dan obesiti.
Pakar perubatan menganggap perut buncit sebagai sarang penyakit! Semua penyakit bermula dari perut. Jika tembolok dilayan dengan sepenuhnya, perut yang besarnya hanya sebesar penumbuk, tidak mampu menjalankan tugasnya dengan sempurna, akibatnya, makanan tidak dapat dicerna sepenuhnya, malah akan terperap, mereput dan membusuk.
Hasilnya sembelit, nafas berbau, peluh berbau dalam jangka masa panjang wujudlah pelbagai penyakit kronik seperti Diabetes, Obesiti, dan kemuncaknya, Barah.
Eucheuma adalah sejenis spesis rumpai laut yang tumbuh liar dalam kelompok yang banyak terutamanya di negeri Sabah, Malaysia Timur. Ianya bleh didapati tumbuh dalam air yang tenang atau medium air yang bergerak perlahan. Kajian saintifik menunjukkan Eucheuma mengandungi bahan berguna yang boleh digunakan dalam proses asas bio-kemikal dan bio-teknologi. Teknologi memelihara dan membangunkan rumpai ini masih dibangunkan lagi untuk mendapatkan hasil yang tinggi dan kualiti yang terbaik. Saya ada melawat projek ini tidak lama dulu dan memang berpotensi untuk pergi lebuh jauh.
SUMBER : BLOGLEPAT
2. Comparison of Tamoxifen with Edible Seaweed (Eucheuma cottonii L.) Extract in Suppressing Breast Tumor.
Source
a Institute of Bioscience , University Putra Malaysia , 43400 Serdang , Selangor , Malaysia.
Abstract
The tropical seaweed (Eucheuma cottonii L.) is rich in nutrients and polyphenolic compounds that may suppress cancer through its antioxidant and antiproliferative properties. The study reports on rat mammary tumor suppression and tissue antioxidant status modulation by E. cottonii ethanol extract (ECE). The effect of orally administered ECE (100 mg/kg body-weight) was compared with that of tamoxifen (10 mg/kg body-weight). Rat was induced to develop mammary tumor with subcutaneous injection of LA-7 cells (6 × 10(6) cells/rat). The ECE was more effective than tamoxifen in suppressing tumor growth (27%), improving tissues (plasma, liver, and kidney) malondialdehyde concentrations, superoxide dismutase activity and erythrocyte glutathione concentrations (P < 0.05). Unlike tamoxifen, the ECE displayed little toxicity to the liver and kidneys. The ECE exhibited strong anticancer effect with enzyme modulating properties, suggesting its potential as a suppressing agent for mammary gland tumor.
SUMBER : NCBI
3. Eucheuma cottoni - A potential natural treatment for breast cancer
The seaweed used in this remarkable study was Eucheuma cottonii L., an edible, tropical seaweed which grows naturally within about 20 degrees of the equator and is most commonly found around Southeast Asia. The Euchema group of seaweeds is already widely commercially farmed for use in the production of carrageenan. Researchers at the University Putra Malaysia harvested the seaweed from the coastal waters of North Borneo during January. The seaweed was shade dried for three days and extracted using an 80 percent ethanol solution which was then evaporated to leave a dry powder extract. The extract was found to be rich in iodine, quercetin, catechin, rutin, carotenoids, and more exotic antioxidants such as phytopheophylin and phlorotannins.
To test the extract against breast cancer, Sprague-Dawley rats were injected with LA-7 breast cancer cells and divided into three groups: one group was not treated at all, the second was treated with the most commonly used breast cancer chemo drug at 10 mg/kg body weight, and the third group was treated with the seaweed extract at 100 mg/kg body weight. According to the researchers, this dose is equivalent to giving a 50 kg woman an 800 mg tablet of the seaweed extract.
To test the extract against breast cancer, Sprague-Dawley rats were injected with LA-7 breast cancer cells and divided into three groups: one group was not treated at all, the second was treated with the most commonly used breast cancer chemo drug at 10 mg/kg body weight, and the third group was treated with the seaweed extract at 100 mg/kg body weight. According to the researchers, this dose is equivalent to giving a 50 kg woman an 800 mg tablet of the seaweed extract.
27 percent more effective than chemo while improving antioxidant status
Rats treated with the chemo drug for four weeks showed a 71 percent decrease in the size of their tumors, but those treated with the seaweed extract had their tumors shrink by 91 percent - an improvement of 27 percent over chemo. The chemo drug also caused significant toxicity to the rats' kidneys and livers, causing visible lesions on those organs. Not only did the seaweedshow no toxicity (no liver or kidney lesions), it actually improved the rats' antioxidant status. MDA (malondialdehyde) is a key marker of oxidative stress, with higher MDA levels indicating increased oxidative damage (MDA levels often rise with cancer). Treatment with the chemo drug decreased rats' MDA levels by 27 percent, but again, the seaweed performed better and decreased MDA levels by 46 percent. Conversely, an important marker of antioxidant status is the glutathione level in erythrocytes (red blood cells), with higher glutathione levels indicating improved antioxidant status. Chemo treated rats saw their levels drop by 57 percent. But glutathione levels actually increased by 78 percent in seaweed treated rats - showing a sizable advantage for antioxidant status.
Seaweed for cancer - an established history
Various seaweeds have been used for centuries in Chinese and Japanese traditional medicine against breast cancer. Epidemiological studies have also showed that daily seaweed consumption may dramatically lower breast cancer risk, and is considered one reason why Japanese women have 83 percent less breast cancer than those in the West. More recently, a clinical trial in the U.S. showed that just five grams per day of dried seaweed (Undaria) decreased levels of a key pro-cancer protein (uPAR) by 47 percent in postmenopausal women.
This new study provides yet more good science to the case for using seaweed against breast cancer. And while this latest seaweed still must be proven out in human patients, it is impressive that the effective dose is likely attainable in human patients, using the extract of a seaweed which has been routinely eaten by Malaysian locals for decades with apparently no ill effects.
This new study provides yet more good science to the case for using seaweed against breast cancer. And while this latest seaweed still must be proven out in human patients, it is impressive that the effective dose is likely attainable in human patients, using the extract of a seaweed which has been routinely eaten by Malaysian locals for decades with apparently no ill effects.
SUMBER : NaturalNews
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